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Last updated 3 days ago
Long-term mesoscale imaging of 3D intercellular dynamics across a mammalian organ
3 days ago
RUSH3D, with the integration of multiple computational imaging methods based on a...
Neoself-antigens are the primary target for autoreactive T cells in human lupus
3 days ago
The discrimination of self- and neoself-antigens by T cells plays a crucial...
Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
3 days ago
Aging-driven and sex-dependent molecular changes in skin fibroblasts drive the emergence of...
m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells
3 days ago
CENPA is an m6A reader with specificity for m6A-modified centromeric RNA. The...
The Fanconi anemia pathway induces chromothripsis and ecDNA-driven cancer drug resistance
3 days ago
A genetic screen uncovers the Fanconi anemia pathway as a driver of...
5-Formylcytosine is an activating epigenetic mark for RNA Pol III during zygotic reprogramming
3 days ago
An open question in epigenetics is if 5-formylcytosine (5fC) is merely a...
A line attractor encoding a persistent internal state requires neuropeptide signaling
3 days ago
Oxytocin and vasopressin receptors are required in the ventromedial hypothalamus for persistent...
Diatom pyrenoids are encased in a protein shell that enables efficient CO2 fixation
3 days ago
Identification and characterization of a protein lattice around the pyrenoid compartments of...
Biomolecular condensates regulate cellular electrochemical equilibria
3 days ago
Biomolecular condensation modulates the electrochemical equilibria of a cell, affecting cytoplasmic ion...
A protein blueprint of the diatom CO2-fixing organelle
3 days ago
A conserved family in the protein interaction network of the CO2-fixing pyrenoid...
Bronze Age cheese reveals human-Lactobacillus interactions over evolutionary history
3 days ago
Ancient DNA has been recovered from Bronze Age cheese residue, revealing cultural...
Divergent sensory pathways of sneezing and coughing
3 days ago
Sneezing and coughing are frequently associated with allergies and respiratory viral infections...